SUTHERLAND LAB
Welcome to the Sutherland Lab in the Department of Biological Sciences at the University of Delaware. We are microbiologists and biochemists who study the fundamental biological processes of cytochrome c biogenesis and heme trafficking in bacteria.
Bacteria are able to survive and thrive in nearly every environment on Earth. This is in part due the plasticity of bacterial respiration and the diversity found in their electron transport chains. Cytochromes c are a key component of many electron transport chains, but also perform other important functions in bacteria. The Sutherland Lab studies cytochrome c biogenesis or how cytochromes c are made by the cell. We use biochemical, molecular biology and microbiology techniques to study this fundamental biological process.
Donna Price was selected as the recipient for the Undergraduate Research Award from the Department of Biological Sciences at the University of Delaware! This annual award is given to a…
Check out our new paper in mBio! This paper biochemically maps the heme transporter for System I cytochrome c biogenesis – CcmCD!
Check out our new technique paper on producing recombinant cytochrome c species in Methods in Molecular Biology!
Check out our new paper in Communications Biology that determines the System II WWD domain has conserved function across bacterial species.
Check out our new mBio paper! This work defines the CcmF WWD domain as a heme binding domain and as critical for cytochrome c biogenesis.
The Sutherland Lab had a great time at the ASBMB Annual Meeting in Chicago IL! Allison presented a poster and Molly gave a talk.